Candesartan ester piece in the body quickly be hydrolyzed into active metabolite candesartan, candesartan for selective angiotensin Ⅱ (AT1) receptor antagonists. So, candesartan ester piece of usage and dosage is?

Candesartan acetate ingredient is: to candesartan ester. Chemical name: (+) - 1 - [[(cyclohexanol oxygen generation) carbonyl] oxygen generation] ethyl - 2 - ethoxy - 1 - [(2 '- (1 h - four nitrogen imidazolyl - 5) - [1, 1' - al phenyl] - 4 - base) methyl] 1 h - benzene and imidazole - 7 - carboxylic acid ester.

Candesartan acetate tablets, the average adult 1, 1, 1 times 4 ~ 8 mg, can increase the dose of 12 mg when necessary.

Candesartan ester piece of drug interaction is: pay attention to and () should be paid attention to when drug combination of this product with glibenclamide, nim horizon, digoxin, warfarin, hydrochlorothiazide and other drugs had no obvious interaction.

Candesartan ester pieces of the following patients should be carefully use:

1. Patients with bilateral or unilateral renal artery.

2. Patients with high potassium.

3. The patients with liver dysfunction (likely worsen liver function. And, presumably active metabolite of candesartan clearance is reduced, thus began to use, should be from small dose drug carefully).

4. Have severe renal dysfunction (due to excessive step-down, may worsen kidney function, so 1, 1, taken from 2 mg, careful medication).

5. Patients with a history of drug allergy.

6. The elderly patients.

7. Renal transplantation: for recent do kidney transplant patients, there is no medication experience.

8. The artery and the left atrioventricular valve stenosis (obstructie cardiac hypertrophy) : patients with using other vasodilator, hemodynamics in patients with artery or left atrioventricular stenosis associated particularly careful or obstructive cardiac hypertrophy patients.

9. Light, moderate adrenal cortical hormone too much, too much light, moderate adrenal cortical hormone, for inhibiting renin - angiotensin and aldosterone system play a role of antihypertensive drugs usually don't respond, so don't take this product.